Bhaktivedanta VedaBase: Śrīmad Bhāgavatam 11.5.17

eta ātma-hano 'śāntā

ajñāne jñāna-māninaḥ

sīdanty akṛta-kṛtyā vai

kāla-dhvasta-manorathāḥ

SYNONYMS

ete — these; ātma-hanaḥ — killers of the self; aśāntāḥ — devoid of peace; ajñāne — in ignorance; jñāna-māninaḥ — presuming to have knowledge; sīdanti — they suffer; akṛta — failing to perform; kṛtyāḥ — their duty; vai — indeed; kāla — by time; dhvasta — destroyed; manaḥ-rathāḥ — their fanciful desires.

TRANSLATION

The killers of the soul are never peaceful, because they consider that human intelligence is ultimately meant for expanding material life. Thus neglecting their real, spiritual duties, they are always in distress. They are filled with great hopes and dreams, but unfortunately these are always destroyed by the inevitable march of time.

PURPORT

There is a similar verse in Śrī Īśopaniṣad (3):

asuryā nāma te lokā

andhena tamasāvṛtāḥ

tāḿs te pretyābhigacchanti

ye ke cātma-hano janāḥ

"The killer of the soul, whoever he may be, must enter into the planets known as the worlds of the faithless, full of darkness and ignorance."

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His Divine Grace A. C. Bhaktivedanta Swami Prabhupāda, Founder Ācārya of the International Society for Krishna Consciousness
His Holiness Hrdayananda dasa Goswami
Gopiparanadhana dasa Adhikari
Dravida dasa Brahmacari