Bhaktivedanta VedaBase: Śrīmad Bhāgavatam 6.1.55

eṣa prakṛti-sańgena

puruṣasya viparyayaḥ

āsīt sa eva na cirād

īśa-sańgād vilīyate

SYNONYMS

eṣaḥ — this; prakṛti-sańgena — because of association with the material nature; puruṣasya — of the living entity; viparyayaḥ — a situation of forgetfulness or an awkward position; āsīt — came to be; saḥ — that position; eva — indeed; na — not; cirāt — taking a long time; īśa-sańgāt — from the association of the Supreme Lord; vilīyate — is vanquished.

TRANSLATION

Since the living entity is associated with material nature, he is in an awkward position, but if in the human form of life he is taught how to associate with the Supreme Personality of Godhead or His devotee, this position can be overcome.

PURPORT

The word prakṛti means material nature, and puruṣa may also refer to the Supreme Personality of Godhead. If one wants to continue his association with prakṛti, the female energy of Kṛṣṇa, and be separated from Kṛṣṇa by the illusion that he is able to enjoy prakṛti, he must continue in his conditional life. If he changes his consciousness, however, and associates with the supreme, original person (puruṣaḿ śāśvatam), or with His associates, he can get out of the entanglement of material nature. As confirmed in Bhagavad-gītā (4.9), janma karma ca me divyam evaḿ yo vetti tattvataḥ: one must simply understand the Supreme Person, Kṛṣṇa, in terms of His form, name, activities and pastimes. This will keep one always in the association of Kṛṣṇa. Tyaktvā dehaḿ punar janma naiti mām eti so'rjuna: [Bg. 4.9] thus after giving up his gross material body, one accepts not another gross body but a spiritual body in which to return home, back to Godhead. Thus one ends the tribulation caused by his association with the material energy. In summary, the living entity is an eternal servant of God, but he comes to the material world and is bound by material conditions because of his desire to lord it over matter. Liberation means giving up this false consciousness and reviving one's original service to the Lord. This return to one's original life is called mukti, as confirmed in Śrīmad-Bhāgavatam (muktir hitvānyathā rūpaḿ svarūpeṇa vyavasthitiḥ).

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His Divine Grace A. C. Bhaktivedanta Swami Prabhupāda, Founder Ācārya of the International Society for Krishna Consciousness